75. En relation avec la connaissance de la substance dopante, la jurisprudence du Tribunal Arbitral du Sport (ci-après : TAS) précise : « One cannot manufacture a substance without knowing the substance that they are manufacturing. The same requirement of knowledge must be present when extracting, transforming or preparing a prohibited substance. What distinguishes any purchase of a substance from one that is prohibited by the definition is knowledge as to what the substance is that one is buying.