alcohol per volume of formulation, at least 1% weight of a pharmaceuticallyacceptable non-aqueous ester solvent miscible in a ricinoleate vehicle per volume of formulation and a sufficient amount of a ricinoleate vehicle so as to prepare a formulation of at least 45 mgml-1 of fulvestrant. with dependent claims 5 to 17 to remain unchanged and claims 18. Use of fulvestrant in the preparation of a pharmaceutical formulation for the treatment of breast cancer by intra-muscular administration to human patients, wherein the pharmaceutical formulation comprises fulvestrant in solution,15-25 % weight of a