"1. The complaint is to be denied. 2. Auxiliary to no. 1 above, the Patent is to be upheld with the following limited claims: 1. Use of fulvestrant in the preparation of a pharmaceutical formulation for the treatment of breast cancer by intra-muscular administration, wherein the formulation comprises fulvestrant in a ricinoleate vehicle, a pharmaceutically acceptable non-aqueous ester solvent, and a pharmaceutically acceptable alcohol, and wherein the formulation is adapted for attaining a therapeutically significant bloodplasma fulvestrant concentration for at least 2 weeks.