"10. A method of manufacturing the free drug particulate form of claim 1
comprising:
(a) providing a solid, free form of the compound in which the compound is
present as solid particles not intimately embedded in a polymeric coprecipitate, and
(b) comminuting the solid free form of the compound to provide particles
of the compound wherein at least 90% of the particles have a particle size
of less than about 40 microns."

Die Klägerin verweist auf S. 15, Zeilen 3-5 der WO 01/08686:

"Lot 1 of Compound A was made using a 12 inch pancake style jet mill
fed at a rate of 28 to 30 kg/hour with sufficient grind pressure to produce
material having a d90 of 4 microns."