Zur Begründung betreffend Verletzung von Art. 123 Abs. 2 EPÜ (unzulässige Erweiterung) führte der Prüfer an:

"The amendments filed with letter 23.12.2004 do not comply with the requirements of Art. 123(2) EPC in so far as they introduce subject matter
beyond the content of the originally filed documents. T The subject matter of present claims 1 reading "use of pemetrexed..." and claim 13 "a
product containing pemetrexed..." do not find base in the application documents as filed. The term "pemetrexed" in the wording of these claims
and the corresponding passages on amended description is certainly a
distinct compound (CAS Registry number 137281-23-3) of the